Article

Laboratory Validation of a Clinical Metagenomic Sequencing Assay for Pathogen Detection in Cerebrospinal Fluid

2018-05-25

Abstract excerpt

<h4>ABSTRACT</h4> Metagenomic next-generation sequencing (mNGS) for pan-pathogen detection has been successfully tested in proof-of-concept case studies in patients with acute illness of unknown etiology, but to date has been largely confined to research settings. Here we developed and validated an mNGS assay for diagnosis of infectious causes of meningitis and encephalitis from cerebrospinal fluid (CSF) in a lic...

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Literature Corpus work: fbd1fda7-979b-5333-86af-48080044c80b
DOI: 10.1101/330381

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