Article

Metagenomics for chronic meningitis: clarifying interpretation and diagnosis

2017-11-07

Abstract excerpt

<h4>Importance</h4> Identifying infectious causes of subacute and chronic meningitis can be challenging. Enhanced, unbiased diagnostic approaches are needed. <h4>Objective</h4> To present a case series of patients with diagnostically challenging subacute and chronic meningitis in whom metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid (CSF), supported by a statistical framework generated from m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 296dceb2-5450-5f2c-9dea-c846a9657a52
DOI: 10.1101/213561

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Metagenomics for chronic meningitis: clarifying interpretation and diagnosisDOI 10.1101/213561Read

Metagenomic Next-generation Sequencing of Cerebrospinal Fluid for the Diagnosis of Central Nervous System Infections: A Multicentre Prospective StudySemantic proximity Read

Uncovering Hidden Pathogens in Culture Negative Cases: Enhancing Diagnostic Utility in Post-Neurosurgical Meningitis/Ventriculitis Using 16S MetagenomicsSemantic proximity Read

Metagenomic Next-generation Sequencing of Cerebrospinal Fluid for the Diagnosis of Central Nervous System Infections: A Multicentre Cohort StudySemantic proximity Read

A Metagenomics – Based Diagnostic Approach for Central Nervous System Infections in Hospital Acute Care SettingSemantic proximity Read

Seven-year performance of a clinical metagenomic next-generation sequencing test for diagnosis of central nervous system infectionsSemantic proximity Read

Metagenomic next-generation sequencing of cerebrospinal fluid for diagnosis of central nervous system infections: 7-year performance of a clinically validated testSemantic proximity Read

Enhanced virus detection and metagenomic sequencing in patients with meningitis and encephalitisSemantic proximity Read

Microbiota Profiling of Cerebrospinal Fluid in Bacterial Meningitis Using 16S rRNA Metagenomic SequencingSemantic proximity Read

Clinical application and evaluation of metagenomic next-generation sequencing in pathogen detection for suspected central nervous system infectionsSemantic proximity Read

Optimization of cerebrospinal fluid microbial metagenomic sequencing diagnosticsSemantic proximity Read

Laboratory Validation of a Clinical Metagenomic Sequencing Assay for Pathogen Detection in Cerebrospinal FluidSemantic proximity Read

Next-generation sequencing in neuropathological diagnosis of infections of the nervous systemSemantic proximity Read