Article

Optimization of cerebrospinal fluid microbial metagenomic sequencing diagnostics

2020-06-25

Abstract excerpt

<h4>Background</h4> Infection in the central nervous system is a severe condition associated with high morbidity and mortality. Despite ample testing, the majority of encephalitis and meningitis cases remain undiagnosed. Metagenomic sequencing of cerebrospinal fluid has emerged as an unbiased approach to identify rare microbes and novel pathogens. However, several major hurdles remains, including establishment of...

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Literature Corpus work: 604fd19c-1a9c-51ea-a03c-170db7f1839b
DOI: 10.1101/2020.06.25.170423

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