Article
Malaria Vaccine: Candidate Antigens, Mechanisms, Constraints and Prospects
18 Sept 2002
Abstract excerpt
More than 30 years after the first report of successful vaccination against malaria using radiation-attenuated sporozoites, an effective malaria vaccine is not yet available. However, field and experimental data indicate that it can be developed. An astonishing amount of data has accumulated concerning parasite biology, host-parasite interactions, immunity and escape mechanisms, targets and modulators of immune...
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