Article

AKR1C3High CAFs located in the Invasive Tumor Front Drive OSCC Progression

2026-06-11

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective</bold> : Cancer-associated fibroblasts (CAFs) play critical roles in oral squamous cell carcinoma (OSCC) progression. Accumulating evidence demonstrates spatial heterogeneity in CAF distribution and function within tumors, however, the spatial distribution of CAFs between the invasive tumor front (ITF) and tumor center (TC), their clinical significance, and underlying...

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Literature Corpus work: e9f8edac-7072-516d-a29a-280cb6933ebd
DOI: 10.21203/rs.3.rs-9514033/v1

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