Article

Lypd6b promotes colon tumorigenesis by inhibiting CD8+ T cell-mediated anti-tumor immunity through metabolic reprogramming

2024-09-23

Abstract excerpt

<title>Abstract</title> <p>Lymphocyte antigen-plasminogen activator urokinase receptor domain-containing protein 6B (Lypd6b) is a newly discovered molecule associated with neuromodulation. However, the specific role of Lypd6b in colorectal cancer (CRC) remains unknown. Here, Lypd6b knockout (Lypd6b−/−) mice were generated and an azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced colitis-associated colorectal...

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Literature Corpus work: e9f71d2b-99e6-5eee-8ed2-4762760ee211
DOI: 10.21203/rs.3.rs-5050970/v1

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