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Article

Creation of Novel Methylating Conjugal Donor Strains for Genetically Recalcitrant Bacteria

2026-01-23

Abstract excerpt

A methodology is presented to integrate DNA methyltransferase genes of interest into the single copy, IncPβ ‘R’ Factor conjugal plasmid, R702. This is to enable DNA transfer, or improved frequency thereof, by mirroring the recipient native DNA methylation signature prior to transfer of plasmid DNA by conjugation, evading native restriction modification systems in the organism of study, without target strain modifi...

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Identifiers and source

Literature Corpus work
e99fb962-4bdd-57fe-8013-e98dbac1b6e3
DOI
10.64898/2026.01.22.701203
Open publication

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Creation of Novel Methylating Conjugal Donor Strains for Genetically Recalcitrant BacteriaDOI 10.64898/2026.01.22.701203
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