Article

Machine Learning-Driven Discovery and Experimental Validation of Novel STING Inhibitors from Traditional Chinese Medicine

2026-04-22

Abstract excerpt

<title>Abstract</title> <p>The stimulator of interferon genes (STING) is a key signaling adaptor in the cGAS-STING pathway of the innate immune system, playing a significant role in autoimmune diseases, viral infections, and cancer, thus representing a promising target for small-molecule inhibitor therapies. This study presents an integrated multi-dimensional computer-aided drug design (CADD) approach that utiliz...

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Literature Corpus work: e96d6c42-409f-5409-a18f-c56bb7ce78b2
DOI: 10.21203/rs.3.rs-9357878/v1

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