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The Presence of HIV-1 and HIV-2 Derived tRNA-like Motifs at Specific Intervals in Human Genes: Implications for the Regulation of Host Splicing

2026-07-15

Abstract excerpt

<title>Abstract</title> <p> Building on the previously proposed <italic>spliceosome antagonism hypothesis</italic> for SARS-CoV-2, this study identifies novel tRNA-like RNA structures in HIV-1 and HIV-2 and examines their distinctive distribution patterns within the human genome. We show that central 8-base motifs derived from HIV-1 (TAGTCTTG) and HIV-2 (CCTGTCTG) occur as paired elements within human introns...

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Literature Corpus work
e95ddd28-dc8d-56b3-b385-6652800bddcc
DOI
10.21203/rs.3.rs-10344835/v1
Open publication

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The Presence of HIV-1 and HIV-2 Derived tRNA-like Motifs at Specific Intervals in Human Genes: Implications for the Regulation of Host SplicingDOI 10.21203/rs.3.rs-10344835/v1
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