Article

APOBEC1 mediated C-to-U RNA editing: target sequence and trans-acting factor contribution to 177 RNA editing events in 119 murine transcripts in-vivo

2021-01-08

Abstract excerpt

<h4>ABSTRACT</h4> Mammalian C-to-U RNA editing was described more than 30 years ago as a single nucleotide modification in APOB RNA in small intestine, later shown to be mediated by the RNA-specific cytidine deaminase APOBEC1. Reports of other examples of C-to-U RNA editing, coupled with the advent of genome-wide transcriptome sequencing, identified an expanded range of APOBEC1 targets. Here we analyze the cis-ac...

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Literature Corpus work: 1f8e22ed-e9b4-5a84-b1bc-0219ecdd8bcc
DOI: 10.1101/2021.01.08.425897

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