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In-depth Bioinformatic Analyses of Human SARS-CoV-2, SARS-CoV, MERS-CoV, and Other <i>Nidovirales</i> Suggest Important Roles of Noncanonical Nucleic Acid Structures in Their Lifecycles

2020-04-11

Abstract excerpt

Noncanonical nucleic acid structures play important roles in the regulation of molecular processes. Considering the importance of the ongoing coronavirus crisis, we decided to evaluate genomes of all coronaviruses sequenced to date (stated more broadly, the order Nidovirales ) to determine if they contain noncanonical nucleic acid structures. We discovered much evidence of putative G-quadruplex sites and even muc...

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Literature Corpus work
844fc301-dccb-593e-8951-4c3ef2d6fca1
DOI
10.1101/2020.04.09.031252
Open publication

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In-depth Bioinformatic Analyses of Human SARS-CoV-2, SARS-CoV, MERS-CoV, and Other <i>Nidovirales</i> Suggest Important Roles of Noncanonical Nucleic Acid Structures in Their LifecyclesDOI 10.1101/2020.04.09.031252
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