Conserved long-range base pairings are associated with pre-mRNA processing of human genes

Abstract excerpt

The ability of nucleic acids to form double-stranded structures is essential for all living systems on Earth. While DNA employs it for genome replication, RNA molecules fold into complicated secondary and tertiary structures. Current knowledge on functional RNA structures in human protein-coding genes is focused on locally-occurring base pairs. However, chemical crosslinking and proximity ligation experiments have...

Topics

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• 3' Untranslated Regions
• Cytoplasm
• Cytoskeletal Proteins
• Nucleic Acid Conformation
• Regulatory Factor X Transcription Factors
• RNA Splicing
• RNA Stability
• X-Box Binding Protein 1

Identifiers and source

Literature Corpus work

8d3c57c2-2ed4-5d16-90b4-0d47e55c6cb4

DOI

10.1101/2020.05.05.076927