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A survey of RNA secondary structural propensity encoded within human herpesvirus genomes: global comparisons and local motifs

10 Sept 2020

Abstract excerpt

There are nine herpesviruses known to infect humans, of which Epstein-Barr virus (EBV) is the most widely distributed (>90% of adults infected). This ubiquitous virus is implicated in a variety of cancers and autoimmune diseases. Previous analyses of the EBV genome revealed numerous regions with evidence of generating unusually stable and conserved RNA secondary structures and led to the discovery of a novel...

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PMID: 32974099
DOI: 10.7717/peerj.9882

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