Article

Facile Method for Delivering Chikungunya Viral Replicons Into Mosquitoes and Mammalian Cells

2021-03-03

Abstract excerpt

Reverse genetics is an important tool in the elucidation of viral replication and the development of countermeasures; however, these methods are impeded by laborious and inefficient replicon delivery methods. This paper demonstrates the use of a baculovirus to facilitate the efficient delivery of autonomous CHIKV replicons into mosquito and mammalian cells in vitro as well as adult mosquitoes in vivo . The efficac...

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Identifiers and source

Literature Corpus work: e94fe60f-8514-5293-870a-94cbb993900b
DOI: 10.21203/rs.3.rs-257201/v1

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