Arboviruses and the Challenge to Establish Systemic and Persistent Infections in Competent Mosquito Vectors: The Interaction With the RNAi Mechanism

Abstract excerpt

Arboviruses are capable to establish long-term persistent infections in mosquitoes that do not affect significantly the physiology of the insect vectors. Arbovirus infections are controlled by the RNAi machinery via the production of viral siRNAs and the formation of RISC complexes targeting viral genomes and mRNAs. Engineered arboviruses that contain cellular gene sequences can therefore be transformed to "viral...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Insect Resistance and Genetics
• Share to Insect symbiosis and bacterial influences
• Share to Mosquito-borne diseases and control