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Preparation and application of chikungunya pseudovirus containing double reporter genes

14 Jun 2022

Abstract excerpt

Abstract Chikungunya virus (CHIKV), a highly infectious and rapidly spread viral pathogen, is classified as a pathogenic agent at the biosafety level 3. Operation of live authentic CHIKV needs a specific laboratory with the P3 or above containment, which greatly confines the CHIKV-associated studies. To establish an evaluation system of CHIKV that can be utilized in a BSL2 laboratory, we constructed a pseudovirus...

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PMID: 35701460
DOI: 10.1038/s41598-022-13230-0

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