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Development of Neutralization Assay Using an eGFP Chikungunya Virus

28 Jun 2016

Abstract excerpt

Chikungunya virus (CHIKV), a member of the Alphavirus genus, is an important human emerging/re-emerging pathogen. Currently, there are no effective antiviral drugs or vaccines against CHIKV infection. Herein, we construct an infectious clone of CHIKV and an eGFP reporter CHIKV (eGFP-CHIKV) with an isolated strain (assigned to Asian lineage) from CHIKV-infected patients. The eGFP-CHIKV reporter virus allows for...

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PMID: 27367716
DOI: 10.3390/v8070181

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