Article

Cardiomyocyte differentiation from iPS cells is delayed following knockout of Bcl-2

2022-01-05

Abstract excerpt

Anti-apoptotic B-cell lymphoma 2 (Bcl-2) regulates a wide array of cellular functions involved in cell death, cell survival decisions and autophagy. Bcl-2 acts by both direct interaction with different components of the pathways involved and by intervening in intracellular Ca 2+ signalling. The function of Bcl-2 is in turn regulated by post-translational modifications including phosphorylation at different sites...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e9402cb0-c4f0-5c25-aa59-52ced346c679
DOI: 10.1101/2022.01.05.475068

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cardiomyocyte differentiation from iPS cells is delayed following knockout of Bcl-2DOI 10.1101/2022.01.05.475068Read

Cardiomyocyte apoptosis in the failing heart — A critical review from definition and classification of cell deathSemantic proximity Read

Sbk2, a Newly Discovered Atrium-Enriched Regulator of Sarcomere IntegritySemantic proximity Read

Developmental Changes in Cardiomyocytes Differentiated from Human Embryonic Stem Cells: A Molecular and Electrophysiological ApproachSemantic proximity Read

Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes.Semantic proximity Read

Concise Review: Maturation Phases of Human Pluripotent Stem Cell-Derived CardiomyocytesSemantic proximity Read

Isl1 Identifies a Cardiac Progenitor Population that Proliferates Prior to Differentiation and Contributes a Majority of Cells to the HeartSemantic proximity Read

What we know about cardiomyocyte dedifferentiationSemantic proximity Read

Cardiomyocyte Death and Genome-Edited Stem Cell Therapy for Ischemic Heart DiseaseSemantic proximity Read

Non-Cardiomyocytes Influence the Electrophysiological Maturation of Human Embryonic Stem Cell-Derived Cardiomyocytes During DifferentiationSemantic proximity Read

Systematic transcriptomic and phenotypic characterization of human and murine cardiac myocyte cell lines and primary cardiomyocytes reveals serious limitations and low resemblances to adult cardiac phenotype.Semantic proximity Read

Myosin light chain 2 marks differentiating ventricular cardiomyocytes derived from human embryonic stem cellsSemantic proximity Read

Generation and primary characterization of iAM-1, a versatile new line of conditionally immortalized atrial myocytes with preserved cardiomyogenic differentiation capacity.Semantic proximity Read