Article

Nickel induced transcriptional changes persist post exposure through epigenetic reprograming

2019-10-17

Abstract excerpt

Nickel is an occupational and environmental toxicant associated with a number of diseases in humans including pulmonary fibrosis, bronchitis and lung and nasal cancers. Our earlier studies showed that the nickel-exposure-induced genome-wide transcriptional changes, which persist even after the termination of exposure may underlie nickel pathogenesis. However, the mechanisms that drive nickel-induced persistent cha...

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Literature Corpus work: e903ff4f-c309-5a55-b78e-13f0c4686e4d
DOI: 10.1101/806588

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