Article

Systems analysis reveals ageing-related perturbations in retinoids and sex hormones in Alzheimer’s and Parkinson’s diseases

2021-06-10

Abstract excerpt

Neurodegenerative diseases (NDDs), including Alzheimer’s (AD) and Parkinson’s diseases (PD), are complex heterogeneous diseases with highly variable patient responses to treatment. Due to the growing evidence for ageing-related clinical and pathological commonalities between AD and PD, these diseases have recently been studied in tandem. In this study, we analyse transcriptomic data from AD and PD patients, and st...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e8bc625f-8691-5ded-bfd7-57f6d9123b07
DOI: 10.1101/2021.06.10.447367

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Systems analysis reveals ageing-related perturbations in retinoids and sex hormones in Alzheimer’s and Parkinson’s diseasesDOI 10.1101/2021.06.10.447367Read

Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer’s and Parkinson’s DiseasesSemantic proximity Read

Multi-omics analysis reveals the genetic aging landscape of Parkinson's disease.Semantic proximity Read

Quantitative Proteomic and Metabolomic Profiling Reveals Altered Mitochondrial Metabolism and Folate Biosynthesis Pathways in the Aging Drosophila EyeSemantic proximity Read

Advancements in multi-omics research to address challenges in Alzheimer’s disease: a systems biology approach utilizing molecular biomarkers and innovative strategiesSemantic proximity Read

In silico analysis to link insulin resistance, obesity, and ageing with Alzheimer’s diseaseSemantic proximity Read

Transcriptomic and Genetic Associations between Alzheimer’s Disease, Parkinson’s Disease, and CancerSemantic proximity Read

The ROSMAP project: aging and neurodegenerative diseases through omic sciencesSemantic proximity Read

Metabolomics of blood reveals age-dependent pathways in Parkinson’s DiseaseSemantic proximity Read

Identification of novel modifiers of Aβ toxicity by transcriptomic analysis in the fruitfly.Semantic proximity Read

Quantitative proteomic and metabolomic profiling reveals altered mitochondrial metabolism and folate biosynthesis pathways in the aging <i>Drosophila</i> eyeSemantic proximity Read

Comparative Proteomic Analysis of Environmental and Genetic Models of Parkinson’s Disease Highlights the Role of Purine MetabolismSemantic proximity Read

Comparative pathway and network analysis of brain transcriptome changes during adult aging and in Parkinson's disease.Semantic proximity Read