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Detection of Mycobacterium tuberculosis DNA in CD34+ peripheral blood mononuclear cells of Ugandan adults with latent infection: a cross-sectional and nested prospective study

2020-07-29

Abstract excerpt

<h4>Background: </h4> : Tuberculin skin test and interferon gamma release assay (IGRA) show limitations in diagnosing latent tuberculosis infection (LTBI) and poorly predict progression to active tuberculosis. This study will explore detection of Mycobacterium tuberculosis ( M.tb ) DNA in CD34 + peripheral blood mononuclear cells (PBMCs) as a biomarker for LTBI and monitoring chemoprophylaxis response. <h4>Met...

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Literature Corpus work
e8af7740-64fd-5b72-a6e4-b7e2e8060b19
DOI
10.12688/aasopenres.13108.1
Open publication

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Detection of Mycobacterium tuberculosis DNA in CD34+ peripheral blood mononuclear cells of Ugandan adults with latent infection: a cross-sectional and nested prospective studyDOI 10.12688/aasopenres.13108.1
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