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Detection of Apparent Cell-free M. tuberculosis DNA from Plasma

8 Jan 2018

Abstract excerpt

New diagnostics are needed to improve clinicians' ability to detect tuberculosis (TB) disease in key populations such as children and persons living with HIV and to rapidly detect drug resistance. Circulating cell-free DNA (ccfDNA) in plasma is a diagnostic target in new obstetric and oncologic applications, but its utility for diagnosing TB is not known. Here we show that Mycobacterium tuberculosis complex DNA...

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PMID: 29330384
DOI: 10.1038/s41598-017-17683-6

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