Article

Systematic Engineering of Virus-Like Particles to Identify Self-Assembly Rules for Shifting Particle Size

2022-09-03

Abstract excerpt

<h4>ABSTRACT</h4> Virus-like particles (VLPs) are promising scaffolds for biomaterials as well as diagnostic and therapeutic applications. However, there are some key challenges to be solved, such as the ability to engineer alternate sizes for varied use cases. To this end, we created a library of MS2 VLP variants at two key residues in the coat protein which have been implicated as important to controlling VLP s...

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Literature Corpus work: e86bfe3a-2dbd-5cbf-a513-48c2f3d5ffe7
DOI: 10.1101/2022.08.31.506130

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