Article

Targeting CHD1L suppresses prostate cancer progression via the FOXO3-PUMA axis

2025-09-03

Abstract excerpt

<title>Abstract</title> <p> Background Prostate cancer (PCa) is one of the most common malignancies in men worldwide, and advanced or metastatic disease remains a major therapeutic challenge. Chromodomain helicase DNA binding protein 1-like (CHD1L) has been implicated as an oncogenic driver in multiple cancer types, yet its role in prostate cancer pathogenesis is not fully defined. The purpose of this study is t...

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Literature Corpus work: e73ee6b6-e1e8-5276-84ad-ac0f12119163
DOI: 10.21203/rs.3.rs-7424447/v1

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