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Integrative CRISPR-Cas9 Screening Reveals Lethal Genes Driving Metastasis and Prognosis in Prostate Adenocarcinoma

2026-03-05

Abstract excerpt

<title>Abstract</title> <p>Prostate adenocarcinoma (PRAD) has become one of the most prevalent malignancies in men worldwide. Although advances in diagnostic techniques and targeted therapies have improved clinical outcomes, a significant subset of patients still develops aggressive, metastatic disease with limited treatment options. At present, identifying reliable biomarkers for early risk stratification remain...

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Literature Corpus work
201cd0ea-bbe1-5c4c-adef-3b6838d808f2
DOI
10.21203/rs.3.rs-8953080/v1
Open publication

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