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Article

CHD1, a multifaceted epigenetic remodeler in prostate cancer

26 Jan 2023

Abstract excerpt

Chromatin remodeling proteins contribute to DNA replication, transcription, repair, and recombination. The chromodomain helicase DNA-binding (CHD) family of remodelers plays crucial roles in embryonic development, hematopoiesis, and neurogenesis. As the founding member, CHD1 is capable of assembling nucleosomes, remodeling chromatin structure, and regulating gene transcription. Dysregulation of CHD1 at genetic,...

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Identifiers

PMID: 36776288
DOI: 10.3389/fonc.2023.1123362

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