Article

No clear evidence for relationships of apolipoprotein E genotype with measures of common infections in three UK cohorts

2026-08-19

Abstract excerpt

Abstract APOE genotype is a very strong genetic risk factor for late-onset Alzheimer’s disease (AD). This relationship may involve mediation by common infections—several of which are also dementia risk factors. We investigated associations of APOE ε2 and ε4 carriage with serostatus and antibody titres to 14 common pathogens in three population-based cohorts (UK Biobank, National Survey of Health and Development, S...

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Literature Corpus work: e738ff0c-79a5-55f7-94ed-5f418193fd8b
DOI: 10.1038/s41598-026-64892-z

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