Article

Identification of an antiretroviral small molecule that appears to be a host-targeting inhibitor of HIV-1 assembly

2020-03-20

Abstract excerpt

<h4>ABSTRACT</h4> Given the projected increase in multidrug resistant HIV-1, there is an urgent need for development of antiretrovirals that act on virus life-cycle stages that are not targeted by antiretrovirals currently in use. Host-targeting drugs are of particular interest because they can offer a high barrier to resistance. Here we report identification of two related small molecules that inhibit HIV-1 late...

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Literature Corpus work: e7115db9-91f6-5b4c-a541-f9d184c45acc
DOI: 10.1101/2020.03.18.998088

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