Article

Nigral iron and neuromelanin studies in Parkinson's disease

2019-01-01

Abstract excerpt

Parkinson’s disease (PD) a neurodegenerative condition characterized by the reduction of the pigmented dopaminergic neurons of the substantia nigra pars compacta (SNc) and the loss of the dopaminergic striatal terminals which in turn result in the cardinal motor symptoms including bradykinesia, rigidity and tremor. Iron plays a deleterious role in the pathophysiology of PD due to the generation of reactive oxidati...

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Literature Corpus work: e6c343e3-87e9-59c8-8110-496a1e5db53f
DOI: 10.25560/77826

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