Article

CroCoNet: a novel framework for cross-species network analysis reveals POU5F1 (OCT4) rewiring

2025-11-18

Abstract excerpt

BACKGROUND: Gene regulatory changes play a central role in shaping cellular phenotypes across species. To understand how these phenotypes evolve, it is essential to investigate the underlying gene regulatory networks (GRNs). However, most comparative analyses of GRNs remain qualitative and are therefore sensitive to false positives and false negatives. RESULTS: To address this limitation, we introduce CroCoNet (...

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Literature Corpus work: e6a07b9e-39ab-5f2b-8806-b686356a4bb1
DOI: 10.1101/2025.11.18.689002

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