Article

STELLAR: A flexible ensemble learning framework integrating rare variants to enhance polygenic risk prediction

2026-06-09

Abstract excerpt

Whole-exome and whole-genome sequencing technology has enabled the discovery of rare genetic variants associated with human health and diseases. However, existing statistical methods used for rare variant association testing are not well-suited for building genetic risk prediction models that jointly incorporate rare and common variants. We propose STELLAR, a flexible ensemble learning-based approach to compute ra...

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Literature Corpus work: e6964336-badd-5637-8ad8-b253a7ade5ef
DOI: 10.64898/2026.06.07.26355109

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