Article

Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments

2020-08-13

Abstract excerpt

<h4>SUMMARY</h4> Functional profiling of a cancer patient’s tumor cells holds potential to tailor personalized cancer treatment. Here we report the utility of Fresh Uncultured Tumor-derived EpCAM+ epithelial Cells (FUTC) for ex vivo drug response interrogation. Analysis of murine Kras mutant FUTCs demonstrated pharmacological and adaptive signaling profiles comparable to subtype-matched cultured cells. Applying...

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Literature Corpus work: e68c6ee3-d3ea-543d-abbb-9c4d869b290d
DOI: 10.1101/2020.08.12.247817

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