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Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week

10 May 2021

Abstract excerpt

While the potential of patient-derived organoids (PDOs) to predict patients' responses to anti-cancer treatments has been well recognized, the lengthy time and the low efficiency in establishing PDOs hamper the implementation of PDO-based drug sensitivity tests in clinics. We first adapt a mechanical sample processing method to generate lung cancer organoids (LCOs) from surgically resected and biopsy tumor...

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PMID: 33972544
DOI: 10.1038/s41467-021-22676-1

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