Article

Glutathione metabolism impacts fungal virulence by modulating the redox environment

2024-02-19

Abstract excerpt

Pathogens must overcome the hostile conditions of their hosts to survive, proliferate and cause disease. The fungal pathogen Cryptococcus neoformans is particularly adept at mitigating challenges in the host environment and has developed an arsenal of defense mechanisms to evade oxidative and nitrosative agents released by phagocytic cells during infection. Among these mechanisms, melanin production is crucially...

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Literature Corpus work: e66608fa-c4c1-592c-a5ae-fa02fe4a2bba
DOI: 10.1101/2024.02.19.581054

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