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Multi-omics characterization of the skin microbiota reveals the anti-aging roles of Stenotrophomonas maltophilia.

Microbiome - 3 Jun 2026

Guo Danni, Chen Yuanyuan, Wu Yahong, Cheng Jingmin, Lin Yawen, Lai Wenjie, Ma Wentao, Yang Hang, Han Lianyi, Ma Lan, Jia Haidong, Liu Xiao

Abstract excerpt

BACKGROUND: Shifts in the skin microbiome have shown a close link to chronological age. However, the contribution of the skin microbiome in skin-aging phenotypes remains unclear. RESULTS: To explore this, we performed phenotypic, metabolomic, metagenomic, and functional analyses on a cohort with divergent skin-aging phenotypes. Genome-scale metabolic models (GEMs) integrated with metabolomic analysis revealed...

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Acinetobacter
Glutathione
Melanins
Metabolomics
Metagenomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Stenotrophomonas maltophilia

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Open in PubMed Open full text

Identifiers

PMID: 42237409
DOI: 10.1186/s40168-026-02433-6
PMCID: PMC13449706

Genes

GCLM
NQO1
PGD
SOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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