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Article

Glutathione biosynthesis in the yeast pathogens Candida glabrata and Candida albicans: essential in C. glabrata, and essential for virulence in C. albicans.

Microbiology (Reading, England) - 1 Feb 2011

Yadav Amit Kumar, Desai Prashant Ramesh, Rai Maruti Nandan, Kaur Rupinder, Ganesan Kaliannan, Bachhawat Anand Kumar

Abstract excerpt

Redox pathways play a key role in pathogenesis. Glutathione, a central molecule in redox homeostasis in yeasts, is an essential metabolite, but its requirements can be met either from endogenous biosynthesis or from the extracellular milieu. In this report we have examined the importance of glutathione biosynthesis in two major human opportunistic fungal pathogens, Candida albicans and Candida glabrata. As the...

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PMID: 20966090
DOI: 10.1099/mic.0.045054-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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