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Photoreceptor layer thinning is an early biomarker for age-related macular degeneration development: Epidemiological and genetic evidence from UK Biobank optical coherence tomography data

2021-08-24

Abstract excerpt

<h4>Introduction</h4> Age-related macular degeneration (AMD) is a blinding condition for which there is currently no early-stage clinical biomarker. AMD is characterized by thinning of the outer retina and drusen formation leading to thickening of the Bruch’s membrane and RPE complex, but the timing between these two events, as well as the role of genetic variants in these processes, are unclear. Here, we jointly...

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Literature Corpus work: e6462182-bc50-531f-8ea1-88a1d2131a57
DOI: 10.1101/2021.08.18.21262226

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