Article

Genetic variation affects morphological retinal phenotypes extracted from UK Biobank Optical Coherence Tomography images

2020-07-26

Abstract excerpt

<h4>ABSTRACT</h4> Optical Coherence Tomography (OCT) enables non-invasive imaging of the retina and is often used to diagnose and manage multiple ophthalmic diseases including glaucoma. We present the first large-scale quantitative genome-wide association study of inner retinal morphology using phenotypes derived from OCT images of 31,434 UK Biobank participants. We identify 46 loci associated with thickness of th...

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Literature Corpus work: 0baa5889-a6b2-5c60-9c02-83c985833664
DOI: 10.1101/2020.07.20.20157180

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