Article
Identifying genetic variants that affect viability in large cohorts
2016-11-07
Abstract excerpt
A number of open questions in human evolutionary genetics would become tractable if we were able to directly measure evolutionary fitness. As a step towards this goal, we developed a method to examine whether individual genetic variants, or sets of genetic variants, currently influence viability. The approach consists in testing whether the frequency of an allele varies across ages, accounting for variation in anc...
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Identifiers and source
- Literature Corpus work
- e61f883c-e62c-5e2d-91ca-9b4fb82aeed1
- DOI
- 10.1101/085969