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Synthesis and Cytotoxic Evaluation of New Fluoro and Trifluoromethyl Substituents Containing Chromeno[2,3‐ d ]pyrimidines

2023-04-04

Abstract excerpt

Abstract In this research, microwave‐assisted “one‐pot” multicomponent reactions have been employed for the synthesis of new chromeno[2,3‐ d ]pyrimidines containing fluorine atoms. The biological significance of the obtained compounds was highlighted by evaluating in vitro for cytotoxic activity against four human cancer cell lines (HepG2, hepatoma carcinoma; MCF7, breast cancer; A549, non‐small lung cancer; KB, e...

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Literature Corpus work
e6165939-ad23-5e31-a6da-70acf9dda919
DOI
10.1002/slct.202300227
Open publication

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Synthesis and Cytotoxic Evaluation of New Fluoro and Trifluoromethyl Substituents Containing Chromeno[2,3‐ d ]pyrimidinesDOI 10.1002/slct.202300227
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