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Article

Diverse reactivity in microwave-promoted catalyst-free coupling of substituted anilines with ethyl trifluoropyruvate and biological evaluation.

Organic & biomolecular chemistry - 14 Sept 2013

Zhang Chen, Zhuang Dao-Min, Li Jia, Chen Si-Yuan, Du Xiao-Long, Wang Jian-Yong, Li Jing-Yun, Jiang Biao, Yao Jian-Hua

Abstract excerpt

Diverse reactivity by coupling of substituted anilines with ethyl trifluoropyruvate was developed under microwave irradiation without catalysts to generate 3-trifluoromethyl-3-hydroxy oxindoles, aromatic hydroxy trifluoromethyl esters, and 1,2-dicarbonyl compounds in a fast and efficient manner. The plausible mechanism for obtaining different products was proposed. Furthermore, the anti-HIV activity of aromatic...

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PMID: 23863885
DOI: 10.1039/c3ob40650d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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