Back to search

Article

TRAF3-Mediated Microglial Reprogramming by Time-Interferential Stimulation Enables Spatioselective Neuronal Rescue Post-Ischemia-Reperfusion 

2026-06-25

Abstract excerpt

<title>Abstract</title> <p> <bold>Background.</bold> Ischemic stroke patients who achieve recanalization still face cerebral ischemia-reperfusion injury (CIRI), an oxidative and inflammatory avalanche for which current therapies offer limited neuroprotection and a narrow therapeutic window. <bold>Objective.</bold> We asked whether temporal-interference stimulation (TIS)-a non-invasive, high-frequency neuromod...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e5ff13f9-d7b3-5081-b499-813a89e21b4a
DOI
10.21203/rs.3.rs-9782588/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
TRAF3-Mediated Microglial Reprogramming by Time-Interferential Stimulation Enables Spatioselective Neuronal Rescue Post-Ischemia-ReperfusionDOI 10.21203/rs.3.rs-9782588/v1
Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after strokeSemantic proximity
Temporal Interference Stimulation Enhances Neural RegenerationSemantic proximity
Omega-3 polyunsaturated fatty acids protect neurological function after traumatic brain injury by suppressing microglial transformation to the proinflammatory phenotype and activating exosomal NGF/TrkA signalingSemantic proximity
Sciatic Nerve Stimulation Attenuates Intracranial Inflammation and Neuronal Injury in Acute Ischemic StrokeSemantic proximity
The Role of Tnf and Soluble Tnf Receptors (TNFR1/2) as Therapeutic Targets for Inflammation Secondary to Intracerebral Stroke and HemorrhageSemantic proximity
NLRP3 inhibition maintains microglia architecture and enhances behavioral recovery after traumatic brain injurySemantic proximity
TLR4-pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injurySemantic proximity
Pulsed Electromagnetic Fields Protect Against Brain Injury After Intracerebral Hemorrhage: Involvement Of Anti-Inflammatory Processes And Hematoma Clearance Via CD36Semantic proximity
Kv1.3 in Microglia Cell Mediates Neurological Dysfunction after Traumatic Brain InjurySemantic proximity
Intranasal CRISPR- lipid nanoparticles targeting MAPK9 reduce neuroinflammation after traumatic brain injurySemantic proximity
Time-dependent dual effect of NLRP3 inflammasome in brain ischemiaSemantic proximity
Remote Ischemic Perconditioning and 90-Day Cognitive Outcomes After Acute Ischemic Stroke: A REMOTE-CAT SubstudySemantic proximity
Select a neighboring publication to make it the new centre.