Article

Photopatterned Membranes and Chemical Gradients Enable Scalable Phenotypic Organization of Primary Human Colon Epithelial Models

2019-09-04

Abstract excerpt

Biochemical gradients across the intestinal epithelium play a major role in governing intestinal stem cell compartmentalization, differentiation dynamics, and organ-level self-renewal. Advances in primary cell-derived in vitro models, in which a full suite of stem and differentiated cell types are present, have vastly accelerated our understanding of intestinal homeostasis and disease. However, scalable plat...

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Literature Corpus work: e59cf93f-bbd3-56f7-a1bc-cddccac9e2fc
DOI: 10.26434/chemrxiv.9759605.v1

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