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Development and Characterization of a Human and Mouse Intestinal Epithelial Cell Monolayer Platform

16 Nov 2017

Abstract excerpt

We describe the development and characterization of a mouse and human epithelial cell monolayer platform of the small and large intestines, with a broad range of potential applications including the discovery and development of minimally systemic drug candidates. Culture conditions for each intestinal segment were optimized by correlating monolayer global gene expression with the corresponding tissue segment. The...

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PMID: 29153987
DOI: 10.1016/j.stemcr.2017.10.013

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