Article
EHMT2/G9a as an Epigenetic Target in Pediatric and Adult Brain Tumors
2021-08-16
Abstract excerpt
Epigenetic mechanisms, including post-translational modifications of DNA and histones that influence chromatin structure, regulate gene expression during normal development, and are also involved in carcinogenesis and cancer progression. The histone methyltransferase G9a (euchromatic histone lysine methyltransferase 2, EHMT2), which mostly mediates mono- and dimethylation by histone H3 lysine 9 (H3K9), influences...
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Identifiers and source
- Literature Corpus work
- e593e4bd-2d32-581a-87c8-c3c8a0dd2f0c
- DOI
- 10.20944/preprints202108.0335.v1
