Article

Molecular mechanism of reward treatment ameliorating chronic stress-induced depressive-like behavior assessed by sequencing miRNA and mRNA in medial prefrontal cortex

2020-05-12

Abstract excerpt

<h4>Background: </h4> Major depressive disorder (MDD) is a disease that seriously endangers human health and mental state. Chronic stress and lack of reward may reduce the function of the brain's reward circuits, leading to major depressive disorder. The effect of reward treatment on chronic stress-induced depression-like behaviors and its molecular mechanism in the brain remain unclear.Methods Mice were divided i...

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Literature Corpus work: e549ad94-30e5-5282-acb4-1dfac53cffc0
DOI: 10.21203/rs.3.rs-23798/v1

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