Article

Osteoblastic PLEKHO1 contributes to joint inflammation in rheumatoid arthritis

2018-07-30

Abstract excerpt

Osteoblasts participating in the inflammation regulation gradually obtain concerns. However, its role in joint inflammation of rheumatoid arthritis (RA) is largely unknown. Pleckstrin homology domain-containing family O member 1 (PLEKHO1) was previously identified as a negative regulator of osteogenic lineage activity. Here we demonstrated that PLEKHO1 was highly expressed in osteoblasts of articular specimens fro...

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Literature Corpus work: e50ea791-c16d-5f61-8dfd-a041655a1462
DOI: 10.1101/380303

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