Article

Duodenal organoids from metabolic dysfunction-associated steatohepatitis patients exhibit altered digestive homeostasis

2024-07-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Aims</h4> Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive liver disease that can lead to fibrosis, cirrhosis, and hepatocellular carcinoma. Though MASH is closely tied to metabolic risk factors, the underlying pathogenic mechanisms remain scarcely understood. Recent research underscores the importance of the gut-liver axis in its pathogenesis, an aspe...

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Literature Corpus work: e4eff0ee-6f3a-5db5-99e4-9b4406ebdcf1
DOI: 10.1101/2024.07.02.601648

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