Article
Organoid Models of Human Gastrointestinal Development and Disease.
Gastroenterology - 1 May 2016
Dedhia Priya H, Bertaux-Skeirik Nina, Zavros Yana, Spence Jason R
Abstract excerpt
We have greatly advanced our ability to grow a diverse range of tissue-derived and pluripotent stem cell-derived gastrointestinal (GI) tissues in vitro. These systems, broadly referred to as organoids, have allowed the field to move away from the often nonphysiological, transformed cell lines that have been used for decades in GI research. Organoids are derived from primary tissues and have the capacity for...
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