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Article

NEK7 is required for G1 progression and procentriole formation

25 May 2017

Abstract excerpt

The decision to commit to the cell cycle is made during G1 through the concerted action of various cyclin–CDK complexes. Not only DNA replication, but also centriole duplication is initiated as cells enter the S-phase. The NIMA-related kinase NEK7 is one of many factors required for proper centriole duplication, as well as for timely cell cycle progression. However, its specific roles in these events are poorly...

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PMID: 28539406
DOI: 10.1091/mbc.e16-09-0643

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